Solid Quality Recombinant Human Serum Albumin Animal Free

Solid quality Recombinant Human Serum Albumin Animal Component Free

Description

Human serum albumin (HSA) is the most abundant protein in plasma with functions of maintaining normal osmolarity in the bloodstream as well as a carrier for numerous small molecules. Clinically, HSA is used to treat acute shock, extensive burn, cirrhotic ascites and hemorrhoea. In bio-industrial, HSA is a valuable bio-material widely used in cell culture media, vaccine, medical devices, cell therapy, small molecular carrier and other bio-pharmaceutical applications. However, the shortage supply of donated blood derived HSA and the potential risk of pathogen infection limits the application of HSA.

OsrHSA, a recombinant human serum albumin independently developed and manufactured by Healthgen Biotech with its core patented Platform Oryz^HiExp: rice endosperm specific expression platform, has been demonstrated to be folded into the identical structure and has equivalent function to plasma human serum albumin(pHSA), as well as the same immunogenicity. So OsrHSA can be an excellent alternative to pHSA.

Using the State-of-the-Art platform Oryz^HiExp to express OsrHSA from rice has solid quality and many advantages, details as follows.

High bioactivity

The recombinant proteins or peptides is expressed in the rice endosperm and stored in the rice protein body which can keep the protein stability and bioactivity to the maximum extent. The OsrHSA has been demonstrated that has equivalent function of pHSA.

High expression level

Patented promotor enable the expression level is 10~1000 times higher over other expression system. With the high expression, the OsrHSA is easier to purify and save the processing cost.

Cost-effective

Rice endosperm platform is cost effective for early stage companies. No enormous investment of bioreactor tanks in the enlarged stage. It enables OsrHSA a favorable price.

Chemical defined

No human derived or animal derived components are involved in the processing, can elimination or reduction of the potential risk of viral and other unknown factors in blood derived products. The OsrHSA is chemical defined, which provides an excellent solution compared with pHSA, BSA or FBS.

Solid quality system

The Healthgen Biotech facility is designed to be cGMP compliant. The quality control system has been certified by ISO 9001: 2015 and ensures standardized process as well as qualified products. The OsrHSA has gained the approval for clincial trials as a primary new drug. Healthgen Biotech will always provide supreme quality OsrHSA based on its quality system.

In conclusion, compared to pHSA, OsrHSA has advantages of animal component free, high bioactivity, high purity, high batch consistency, high capacity, stable supply and cost effective, which can effectively solve the problem of the shortage supply of donated blood derived HSA and eliminate the potential risk of pathogen infection limits the application of HSA.