Oryza Sativa Recombinant Human Albumin For Diagnostics CAS No.70024 90 7

Recombinant human albumin powder for diagnostics

As the most abundant protein in human plasma, human serum albumin (HSA) is composed of 585 amino acids. It has a molecular weight of 66.5KD and an isoelectric point of 4.8. HSA is extensively used in clinics to treat a variety of diseases, such as hypoproteinemia, hemorrhagic shock, serious burn injuries, cirrhotic ascites and fetal erythroblastosis. HSA is an acidic, very soluble protein that is extremely robust: it is stable in the pH range of 4–9, soluble in 40% ethanol. HSA is also widely used in diagnostics because of its non-toxicity, non-enzymatic activity, non-immunogenicity and anti-oxidation.

Currently, HSA is only obtained from human plasma, which is limited in supply but of high pharmaceutical demand. Furthermore, there are other impact may caused by the plasma derived components, potential risks from plasma infectious pathogens, batches varies because of the serum quality changes from different batches, more and more companies prefer to the recombinant human albumin that is animal component free and can increase precision and sensitivity in diagnostics.

Healthgen Biotech recombinant human albumin (OsrHSA) has been successfully produced using a patented rice endosperm. The OsrHSA, which is animal component free, can avoid the prions or virus contaminants, purity is more than 99.99% and endotoxin is less than 0.01EU/mg. The OsrHSA is a quite stable protein that can be heated at 57 °C for up to 10 h without deleterious effects.

Physiological and Biochemical Properties of OsrHSA and pHSA

The recombinant human albumin (OsrHSA), derived from plant, is animal free and can avoid any other plasma derived protein impurity. Using the world leading purification technology, our rHSA has higer than 99% purity and stable batch consistency. OsrHSA can help to increase precision and sensitivity in diagnostic use.