29kD Recombinant Proteinase K Stock Solution 20mg/ml For Automatic Extraction

The automated extraction systems can streamline the tasks involved in extracting nucleic acid from a sample, such as serial dilution and cherry picking. Systems typically also include functions such as shaking, temperature control, and PCR protocols. Fully automated system for nucleic acid extraction and rapid isolation of DNA or RNA from a variety of samples. When the COVID-19 is raging around the world in 2020, the automatic extraction has played a very important role in the detection of COVID-19 nucleic acid. It can achieve large-throughput nucleic acid extraction and complete nucleic acid detection in a short time. It has made a great contribution to the global screening of COVID-19 patients.

The proteinase K possesses a high specific activity which remains stable over a wide range of temperatures and pH values with substantially increased activity at higher temperature. Because it is a a broad-spectrum serine protease, and has no significant substrate specificity. Proteinase K was used widely in COVID-19 nucleic acid automatic extraction, which help to isolate of highly native, undamaged nucleic acid and improve the detection accuracy.

Healthegn Biotech express and purify the recombinant proteinase K (rProK) from yeast (Pichia Pastoris) based on the optimized gene of Engyodontium album by site-directed mutation. The rProK possesses a high specific activity which remains stable over a wide range of temperatures and pH values with substantially increased activity at higher temperature. Purified by chromatography process, the rProK has a high purity more than 95%, which is also completely free of DNase and RNase activities.