OryzHiExp Expression Platform For Recombinant Protein Service GMP compliance Facility

Oryz^HiExp Recombinant Protein Service For Transgenic Animal / Plant

Overview  

Oryz^HiExp of Wuhan Healthgen Biotechnology Corp. is a rice endosperm specific expression platform. With the use of molecular biology, genetic engineering and DNA recombinant technology,

Oryz^HiExp platform uses the rice endosperm cells as a bioreactor to specificly express various recombinant proteins and small peptides. This platform can solve the problems of low expression and large-scale production difficulties in other expression systems; Protein purification technology platform can provide small tests and pilot technology research services to help customers solve the technical problems in protein purification. Particularly, it can provide high-purity pre-clinical protein samples for some small and medium-sized customers.

E AKTA protein purification system, with many specifications from 0.8, 1.6, 2.6, 5 cm, column diameter and height of low pressure column chromatography, meet the demand of protein purification technology development.

The key benefits of Oryz^HiExp:

1. High expression level:

The expression level reaches 0.2~0.8% of the brown rice, which is 10~1000 times higher over other expression level.

2. High bio-activity:

The antitrypsin product expressed by Oryz^HiExp platform is 7.8% to 74.4% more active than the products currently available on the market.

3. Lower production cost:

It is only 2~10% cost over yeast or bacteria fermentation, and 0.01~0.05% cost over animal cell culture.

4. Scalability:

Once getting the homozygous transgenic rice line, it can obtain the kilo level recombinant protein within 2 years.

5. Safety:

It is free of animal-origin pathogens, avoiding the risks from etiology. So it completely avoids the risk.of animal components or viruses, pathogens pathophoresis through pharmaceutical products.

6. Easy for storage and transportation:

The storage and transportation of raw materials are not restricted by time and space.

7. Low carbon and environment friendly:

It saves more energy and raw materials than the traditional medicine industry. It is in line with the low-carbon and environmental friendly concept in modern industry.

Oryz^HiExp collaboration service:

Oryz^HiExp platform can achieve protein and polypeptide expression technology services, Including the construction of vectors, access to high performance and genetically stable transgenic lines; It can also provide downstream purification service of proteins and peptides in small test, pilot process development and other technical services.