Greater Than 90% Purity Recombinant IGF 1 Long R3 Growth Factor Promoting Cell Growth

Greater Than 90% Purity Recombinant IGF 1 Long R3 Growth Factor Promoting Cell Growth

Description 

IGF-1 is a kind of active growth factor, which is the autocrine and paracrine product of dozens of the human liver cells, kidney cells, spleen cells and other cells. Compared with IGF-1, IGF-1 LR3 has 13 more amino acids at the N-terminal, greatly increasing the structural stability and bioactivity. IGF-1 LR3 produced by Healthgen Bichtech has higher purity and activity than many similar products on the market. It can effectively stimulate the AKT signaling pathway, cell growth and proliferation.

Quick Details

1. Other Names: rhIGF-1 LR3, Recombinant IGF 1 Long R3, Long R3 IGF-1, LR3 IGF-1
2. Place of Origin: Wuhan, China (Mainland)
3. Brand Name: Oryzogen
4. Model Number: HYC007M01
5. Source: Yeast
6. Physical Appearance: White lyophilized powder
7. Formulation: rhIGF-1 LR3 is lyophilized with saline.
8. Biological activity: The ED50 is ≤1ng/ml determined by a cell proliferation assay using

Advantages

1. The chairman of Healthgen Biotech Professor Daichang.Yang is one of China's chief scientists. Professor Yang has rechieved the “Thousand Talents program” of the National Central Organization Department, "Hundred Talents Program" of the Organization Department of Hubei Province and Top 10 "Venture Eagle" entrepreneurs.

With years of effort, Healthgen Biotech has developed the State-of-the-Art platform called Oryz^HiExp, having high capacity to express no animal origin proteins and peptides in the rice endosperm cells.

2. Healthgen Biotech rhIGF-1 LR3 is free of animal origin, which effectively avoid any potential risk of animal bacteria, prions, virus and contagious protein disease.

3. The rice endosperm specific expression platform is easy to be large-scale. The rice endosperm has the protein body, which can keeps proteins stability and bioactivity. At present, the production capacity is almost 1 kg / year.

4. Wuhan Healthgen Biotechnology Corp. has strong technical capacity, advanced and complete protein expression and purification technology. Independent research and development, pioneering and internationally advanced State-of-the-art platform called Oryz^HiExp has many advantages, such as high security, easy to scale, simple production process, green and environmental protection. Our company ensures standardized process as well as qualified products. We have established the world's largest large-scale production line with most advanced facilities of plant-origin protein. rhIGF-1 LR3 originated from rice, began in nature.

Supplemental Description

Human Long Arg3 Insulin-like Growth Factor-1(Long-R3-IGF-1) is an 83 amiao acid analog of human IGF-1 comprising the complete human IGF-1 sequence with the substitution of an Arg for the Glu at position 3(hence R3), and a 13 amino acid extension peptide at the N-terminus. Scientists have engineered this analog with the express purpose of increasing biological activity. Human Long-R3-IGF-1 is significantly more potent than human IGF-1 in vitro. The enhanced potency is due to the markedly decreased binding of human Long-R3-IGF-1 to IGF binding proteins which normally inhibit the biological actions of IGFs.