High Bioactivity Recombinant IGF 1 Long R3 Lyophilized With Mannitol Stabilizer

High Bioactivity Recombinant IGF 1 Long R3 Lyophilized With Mannitol Stabilizer​

Description

IGF-1 LR3 is a kind of hormone whose molecular structure is similar to insulin. The main mechanism of IGF-1 LR3 is that it bind to specific receptor (IGF1R) to induce intracellular signal transduction. Compared with IGF-1, IGF-1 LR3 has 13 more amino acids at the N-terminal, greatly increasing the structural stability and maintaining the high bioactivity. Its biological activity is 10 times that of IGF-1, 200-1000 times higher than insulin, which can reach 1 × 106 IU / mg.

Quick Details

1. Other Names: rhIGF-1 LR3, rRecombinant IGF 1 Long R3, Long R3 IGF-1, LR3 IGF-1
2. Place of Origin: Wuhan, China (Mainland)
3. Brand Name: Oryzogen
4. Model Number: HYC007M01
5. Purity: Greater than 90% as determined by SDS-PAGE
6. Physical Appearance: White lyophilized powder
7. Formulation: rhIGF-1 LR3 is lyophilized with saline.
8. Biological activity: The ED50 is ≤1ng/ml determined by a cell proliferation assay using

Advantages

1. Wuhan Healthgen Biotechnology Corp. is a private company founded in 2006. We specialize in molecular pharmaceutical technology research and high-tech innovation-oriented product development, which is developing, manufacturing and marketing a series of recombinant proteins and growth factors by rice endosperm platform. We have 400 square meters of research center, in which 30% of the research personnels have doctoral degree and major in different directions of the research and development. Healthgen Biotech has strong capability in developing a series of biological products.

2. Healthgen Biotech rhIGF-1 LR3 has excellent batch consistency. Using self-pollination rice as the bioreactor to express the rhIGF-1 LR3 with the world's advanced facility and top production proceeding to extract and purify the rhIGF-1 LR3, Healthgen Biotech can ensure the excellent consistency of rhIGF-1 LR3 from different batches.

3. The rice endosperm specific expression platform is easy to be large-scale. The rice endosperm has the protein body, which can keeps proteins stability and bioactivity. At present, the production capacity is almost 1 kg / year.

4. Wuhan Healthgen Biotechnology Corp. has strong technical capacity, advanced and complete protein expression and purification technology. Independent research and development, pioneering and internationally advanced State-of-the-art platform called Oryz^HiExp has many advantages, such as high security, easy to scale, simple production process, green and environmental protection. Our company ensures standardized process as well as qualified products. We have established the world's largest large-scale production line with most advanced facilities of plant-origin protein. rhIGF-1 LR3 originated from rice, began in nature.

Supplemental Description

The lyophilized powder rhIGF-1 LR3 can keep the stability and bioactivity. The lyophilized powder effectively prevents the changes of physical, chemical properties and biological characteristics of rhIGF-1 LR3. It has small damage to biological structure and characteristics of the dormant state and can make them quickly enter the sleep state. So the rhIGF-1 LR3 freeze-dried powder can be stored at -20 ℃ for more than 24 months. The appearance of our rhIGF-1 LR3 powder is white color, which is the same as the rhIGF-1 LR3 derived from E.coli. The rhIGF-1 LR3 was expressed from the rice endosperm, which is much safer than the E.coli derived rhIGF-1 LR3.