Product Details:
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Physical Appearance: | White Lyophilized Powder | Formulation: | RhEGF Is Lyophilized With Mannitol As The Stabilizer |
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Purity: | Greater Than 98% | Usage: | Cosmetics , Cell Culture |
PH: | 6.5-7.5 | Production Type: | Recombinant Protein |
Highlight: | Yeast Derived Epidermal Growth Factors,Recombinant Epidermal Growth Factors,recombinant human epidermal growth factor |
Yeast Derived Recombinant Epidermal Growth Factors EGF Animal Free Lyophilized Powder
Description
The molecular weight of EGF is 6.3 kD. EGF contains 53 amino acids and 3 disulfide bonds in molecule. When EGF binds to the receptor EGFR on the cell surface, it causes a series of biochemical reactions in the cell: improve intracellular calcium concentration, promote the progress of glycolysis, increase protein synthesis, and enhance the specificity of EGFR gene expression to facilitate DNA synthesis and cell proliferation. rhEGF was used in the in vitro for cell culture that can promote cell growth. Meanwhile, Healthgen rEGF has excellent batch consistency and high purity, which will quite useful for the cell culture.
Quick detail
Physiological and Biochemical Properties of our rhEGF and rEGF(E.coli)
Char. | rhEGF | rEGF(E.coli) |
Amino Acids Sequence | Same | Same |
N-terminus | ASTPG | ASTPG |
C-terminus | ALGTTALAATG | ALGTTALAATG |
Molecular Mass(MALDI) | 6.3KD | 6.3KD |
Bioactivity | >1*106IU/mg | >1*106IU/mg |
Purity | >98% | >95% |
Endotoxin | <1.0 EU/mg | <10EU/mg |
Advantages
1. Healthgen Biotech has a professional quality control department, in which 50% of them have master's degree or higher. There are 14 employees in the quality department, 9 of them are in QA and 5 are in QA. All of them have rich experience in analysis research or quality inspection. Half of them have graduated diploma. Every year there are more than 50 training courses, which cover GMP, SOP, specification, hygiene, QA, QC issues, etc.
We strictly control the quality of our products to ensure that all products into the market will be in line with quality standards.
Healthgen Biotech has a series of instruments, which are listed as below.
Equipment | Origin |
Microplate reader | Bio-Tek |
Osmotic pressure detector | Tianjin SMC30C-1 |
Liquid Chromatograph | Agilent |
Gas Chromatograph | PE |
Kjeldahl apparatus | Jinan K9840 |
RT-PCR | ABI |
Karl fischer moisture meter | Mettler Toledo |
Atomic absorption instrument | PE |
2. The lyophilized powder rhEGF can keep the stability and bioactivity. The lyophilized powder effectively prevents the changes of physical, chemical properties and biological characteristics of rEGF. It has small damage to biological structure and characteristics of the dormant state and can make them quickly enter the sleep state. So the EGF freeze-dried powder can be stored at -20 ℃ for more than 24 months. The appearance of our rhEGF powder is white color, which is the same as the EGF derived from E.coli.
3. Healthgen Biotech recombinant Human Epidermal Growth Factor is free of animal origin, which effectively avoid any potential risk of animal bacteria, prions, virus and contagious protein disease.
Supplemental Description
EGF is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. This receptor also binds with TGF-α and VGF (vaccinia virus growth factor). Recombinant human EGF is a 6.3 kDa globular protein containing 53 amino acid residues including 3 intramolecular disulfide-bonds. It was manufactured using all non-animal reagents.
Contact Person: Ms. Abby
Tel: +86-15071115810
Fax: 86-27-59403933-59416006