Animal Free Recombinant Lysozyme High Purity 14.7kD Recombinant protein

Animal-free high purity recombinant lysozyme

Description

Lysozyme (LYZ) is an antimicrobial enzyme produced by animals that forms part of the innate immune system. LYZ is a glycoside hydrolase that catalyzes the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in peptidoglycan, which is the major component of gram-positive bacterial cell wall. This hydrolysis in turn compromises the integrity of bacterial cell walls causing lysis of the bacteria. As Nature's Antimicrobial, lysozyme is a key element in the immune system's fight against infection. This natural polypeptide with a molecular weight of 14,3kDa is naturally present in mother's milk, tears, saliva.

Currently, the commercial lysozyme is mainly produced from milk, which however is limited by the availability of supply and source. The recombinant lysozyme (OsrhLYZ) was expressed in the patented rice endosperm, which is animal component free and has very good batch consistency. The rice endosperm advantages are over other systems in terms of scalability, safety, and cost-effectiveness. The OsrhLYZ purity is higher than 90% and bioactivity is more than 4X10^4 IU/mg. The OsrhLYZ has been demonstrated that has the same physical and chemical with the native lysozyme.

Physical Appearance: Pink beige lyophilized powder

Biological Activity: more than 4X10^4 IU/mg

Purity: More than 90% as determined by SDS-PAGE and HPLC analysis.

Storage condition: Stored in 2~8℃

Reconstitution: PBS or Normal Saline

The purity of OsrhLYZ is more than 90%, showing a single band in SDS-PAGE.

OsrhLYZ has high antimicrobial bioactivity, has non-toxicity in combination with other synergic compounds. In addtion, OsrhLYZ is thermally stable, with a melting point reaching up to 72 ℃ at pH 5.0. OsrhLYZ can be used in varies application:

• Health food--- can be added to baby formula and gastrointestinal treatments for the elderly to preservative against the spoiling microorganisms.
• Skin Care--- can be used cure and prevent acne and bed sores in skin care product.
• Food preservatives---can be a natural antimicrobial enzyme preservative for fruits & vegetables, seafood & meats, wines, to increase a healthy shelf life and augment food safety.
• Soft contact lenses---OsrhLYZ can freely move through the lens, and antibacterial function can reduce the bacterial adhesion, increase the wettability and comfort.