ISO Certificated Recombinant Serum Albumin HSA Derived From Rice Has High Purity

ISO Certificated Recombinant Serum Albumin HSA derived from rice has high purity

Description

Human serum albumin has been widely used as plasma expansion reagent. Because of its non-enzymatic activity and no immunogenicity, etc. HSA can also be used as excipient and stabilizer in a variety of pharmaceutical preparations and serum-free component. In addition, HSA is also used as a drug carrier due to its antioxidant properties, thereby conferring drugs better physicochemical properties. At present, most HSA products in the market are directly derived from human plasma.

On the one hand, due to the potential existence of various infectious disease pathogens in the human blood, especially AIDS, hepatitis B and other viruses. Thereby, these virus from human plasma will be brought with HSA to the final products. rHSA produced by plant derived recombinant proteins technology can effectively avoid the risks of virus pollution and infection. What’s more, the supply of human blood is limited. Therefore, it’s very urgent to search blood substitutes. The establishment and development of recombinant technology provide an important method for the acquisition of biological materials. In recent years, many researchers have been hotly committed to the recombinant human serum albumin research.

Wuhan Healthgen Biotechnology Corp. has been committed in research of protein purification, meanwhile our technology has been patented by the US Patent and Trademark Office on May 15th 2015 and been granted the patent of "A method for isolating and purifying recombinant human serum albumin from transgenic rice grain", which patent number is US9, 023,990. Now, our rHSA purity can be higher than 99%.

Physiological and Biochemical Properties of rHSA and pHSA are showed as below:

Supplemental Description

Healthgen Biotech has strong technical force and advanced and complete protein expression and purification technology development and large-scale production facilities. Self-developed rice endosperm cell expression platform (Oryz^HiExp), which is domestic initiative and the international leader, has such advantages: high expression level, safety, scale-up easily, simple production process and environmental protection etc. After 10 years of unremitting efforts, Healthgen Biotech has established recombinant protein expression and purification technology platform to customize recombinant protein or peptide expression and purification process service for pharmaceuticals, health products, scientific research and industrial reagents. Using the Oryz^HiExp platform, Healthgen Biotech has achievements in developing and commercializing a series of medium ingredients, including recombinant human serum albumin(OsrHSA), recombinant α-1 antitrypsin(OsrhAAT), recombinant human lactoferrin(OsrhLF), recombinant human basic fibroblast growth factor (OsrhbFGF), recombinant human insulin-like growth factor-1 LR3(rhIGF-1 LR3) , recombinant human epidermal growth factor(rhEGF) and recombinant human fibronectin(OsrhFN), which can provide a full set of solutions for animal component free .