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Source: | Rice Grain (Oryza Sativa) | CAS No.: | 70024-90-7 |
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Purity: | Greater Than 99% | Endotoxin: | Less Than 0.125EU/mg |
Formulation: | No Stabilizer Or Surface Active Agent | Amino Acids Sequence: | Same As The HSA From Plasma |
Highlight: | 99% Purity Recombinant Serum Albumin,Low Endotoxin Recombinant Serum Albumin,Low Endotoxin Recombinant Albumin |
99% purity Recombinant Serum Albumin HSA Lyophilized powder low endotoxin
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Description
Human serum albumin is the most abundant protein in human plasma. It can transport hormones, lipds and other molecules and maintain osmotic pressure. Animal free rHSA is a recombinant human serum derived from rice grains, and doesn't contain any animal component, which is much safer than plasma derived HSA.
In the research of protein purification, our technology has been patented by the US Patent and Trademark Office on May 15th 2015. "A method for isolating and purifying recombinant human serum albumin from transgenic rice grain". The patent number is US9, 023,990. Now, our rHSA purity can be higher than 99%.
Endotoxin is a gram-negative bacterium in the cell wall of a component known as lipopolysaccharide. Lipopolysaccharide is toxic to the host. These toxic reactions mainly perform fever reaction, leukocyte reaction and endotoxin shock. Endotoxin is not a protein, so it is very heat-resistant. Its structure won't be broken down by heating at 100 ° C for 1 hour. Only in very special condition, by heating at 160 ° C for 2 to 4 hours or by boiling with strong alkali, strong acid or strong oxidizing agent for 30 minutes,it can be destroyed. Therefore, developing, manufacturing and marketing low endotoxin products are very necessary. Our rHSA endotoxin is less than 0.125 EU / mg.
Healthgen Biotech is compliant with GMP standard. Our raw material, stuff, facility , process packing, transportation and quality control are certified by the relevant state laws and regulations to achieve health quality requirements. The final quality can be entirely ensured.The rHSA has been registered in US FDA as DMF. The DMF no. is 029 648.
Physical Appearance: Off-white to light beige lyophilized powder
Formulation: No stabilizer or surface active agent
Purity: More than 99% as determined by SDS-PAGE and HPLC analysis.
Endotoxin: Less than 0.125EU/mg
Compared with the HSA from plasma, rHSA amino acid sequence entirely. The the secondary and tertiary structure of OsrHSA are identical to those of pHSA. Spectroscopic analysis further confirmed that OsrHSA has the same conformation as pHSA. In terms of immunogenicity and protein activity, rHSA is superior to pHSA and can be used in various fields instead of pHSA.
Physiological and Biochemical Properties of rHSA and pHSA
Char. | pHSA | rHSA |
Amino Acids Sequence | Same | Same |
N-terminus | DAHKSEV | DAHKSEV |
C-terminus | KLVAASQAALGL | KLVAASQAALGL |
Glycosylation | No | No |
Molecular Mass(MALDI) | 66.554KD | 66.550KD |
PI | 4.8 | 4.8 |
Crystal Structure | Identical | Identical |
Contact Person: Ms. Abby
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