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Source: | Rice Grain (Oryza Sativa) | Molecular Weight: | 66.5kD |
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CAS No.: | 70024-90-7 | Formulation: | No Stabilizer Or Surface Active Agent |
Purity: | Greater Than 99% | Production Style: | Recombinant Protein |
Highlight: | 66.5 kD Recombinant HSA,Animal Component Free Recombinant HSA,50g Recombinant HSA |
66.5kD recombinant human serum albumin HSA has 585 amino acids is animal component free
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Description
Healthgen Biotech recombinant human serum albumin (OsrHSA) has excellent batch consistency. Using self-pollination rice as the bioreactor to express the OsrHSA, with the world's advanced facility and top production proceeding to extract and purify the OsrHSA, Healthgen Biotech can ensure the excellent consistency of OsrHSA from different batches. OsrHSA is animal origin free, which effectively avoid any potential risk of animal contaminants, bacteria, prions, virus and contagious protein disease.
Wuhan Healthgen Biotechnology Corp. has been committed in research of protein purification, meanwhile our technology has been patented by the US Patent and Trademark Office on May 15th 2015 and been granted the patent of "A method for isolating and purifying recombinant human serum albumin from transgenic rice grain", which patent number is US9, 023,990. Now, our rHSA purity can be as high as 99%.
Healthgen Biotech is compliant with GMP standard. Our raw material, stuff, facility , process packing, transportation and quality control are certified by the relevant state laws and regulations to achieve health quality requirements. The final quality can be entirely ensured.The OsrHSA has been registered in US FDA as DMF.The DMF no. is 029 648.
Compared with the HSA from plasma, OsrHSA amino acid sequence entirely. The the secondary and tertiary structure of OsrHSA are identical to those of pHSA. Spectroscopic analysis further confirmed that OsrHSA has the same conformation as pHSA. In terms of immunogenicity and protein activity, rHSA is superior to pHSA and can be used in various fields instead of pHSA.
Physiological and Biochemical Properties of rHSA and pHSA
Char. | pHSA | rHSA |
Amino Acids Sequence | Same | Same |
N-terminus | DAHKSEV | DAHKSEV |
C-terminus | KLVAASQAALGL | KLVAASQAALGL |
Glycosylation | No | No |
Molecular Mass(MALDI) | 66.554KD | 66.550KD |
PI | 4.8 | 4.8 |
Crystal Structure | Identical | Identical |
Supplemental Description
Healthgen Biotech has strong technical force and advanced and complete protein expression and purification technology development and large-scale production facilities. Self-developed rice endosperm cell expression platform (OryzHiExp), which is domestic initiative and the international leader, has such advantages: high expression level, safety, scale-up easily, simple production process and environmental protection etc. After 10 years of unremitting efforts, Healthgen Biotech has established recombinant protein expression and purification technology platform to customize recombinant protein or peptide expression and purification process service for pharmaceuticals, health products, scientific research and industrial reagents. Using the OryzHiExp platform, Healthgen Biotech has achievements in developing and commercializing a series of medium ingredients, including recombinant human serum albumin(OsrHSA), recombinant α-1 antitrypsin(OsrhAAT), recombinant human lactoferrin(OsrhLF), recombinant human basic fibroblast growth factor (OsrhbFGF), recombinant human insulin-like growth factor-1 LR3(rhIGF-1 LR3) , recombinant human epidermal growth factor(rhEGF) and recombinant human fibronectin(OsrhFN), which can provide a full set of solutions for animal component free .
Contact Person: Ms. Abby
Tel: +86-15071115810
Fax: 86-27-59403933-59416006