CAS 70024-90-7 Recombinant HSA 66.550KD Lyophilized Without Stabilizer Or Surface Active Agent

CAS 70024-90-7 Recombinant Human Serum Albumin HSA 66.550KD Lyophilized Without stabilizer or surface active agent

Quick detail

1. CAS No.: 70024-90-7
2. Other Names: Recombinant HSA, rHSA, OsrHSA
3. EINECS No.: 274-272-6
4. Place of Origin: Wuhan, China (Mainland)
5. Brand Name: Oryzogen
6. Storage and Handling: Stored at temperatures 2-8℃ for 48 months
7. Model Number: HYC002M01
8. Purity: Greater than 99 % as determined by SDS-PAGE
9. Molecular Mass(MALDI): 66.554KDa
10. Glycosylation: No

Physiological and Biochemical Properties of rHSA and pHSA

Description

Compared with the HSA from plasma, rHSA amino acid sequence entirely. The the secondary and tertiary structure of OsrHSA are identical to those of pHSA. Spectroscopic analysis further confirmed that OsrHSA has the same conformation as pHSA. In terms of immunogenicity and protein activity, rHSA is superior to pHSA and can be used in various fields instead of pHSA.

Human serum albumin is derived from human plasma, which is collected from different human bodies. So we can not guarantee the stability of human serum albumin from different batches. Because of this, it is difficult to apply to large-scale application in vaccine production and cell culture. Healthgen Biotech uses State-of-the-art platform rice endosperm cells as the bioreactor to express the human serum albumin. The platform have high capacity and stable storage protein body to express and storage the proteins and peptides in the rice grain.Rice endosperm cells can specifically and highly express various recombinant proteins and small peptides. By using homozygous rice as the raw material, with the world's top production process, Healthgen Biotech can maximize the stability of albumin batches to meet the needs of industrial production.

Advantages

1. Healthgen Biotech recombinant human serum albumin (OsrHSA) has excellent batch consistency. Using self-pollination rice as the bioreactor to express the OsrHSA, with the world's advanced facility and top production proceeding to extract and purify the OsrHSA, Healthgen Biotech can ensure the excellent consistency of OsrHSA from different batches.

2. The rice endosperm specific expression platform is easy to be large-scale. The rice endosperm has the protein body, which can keeps proteins stability and bioactivity.

At present, the production capacity is almost 1000 kg / year.

3. Recombinant human serum albumin (OsrHSA) has good efficacy, such as OsrHSA has the same second and tertiary structure, physiological and biochemical properties with HSA from plasma. In addition, compared with HSA from plasma, OsrHSA has a lower immune source stimulation, and plays a better role in accelerating cell growth and metabolism, because OsrHSA is animal component free, which can avoid the prions or virus contaminants.