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Source: | Rice Grain(Oryza Sativa) | Endotoxin: | Less Than 0.125EU/mg |
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Usage: | Cell Culture, Stem Cell Culture, Vaccine Reseach | CAS No.: | 70024-90-7 |
Sterility Test: | Sterile | Abnormal Toxicity Test: | Conforms To Standard |
Highlight: | Recombinant Human Albumin Light Beige,Recombinant HSA 7.4 PH,rHSA 7.4 PH |
Lyophilized Powder Recombinant Human Serum Albumin HSA Light Beige Color 6.4-7.4 PH
Quick dtail
Physiological and Biochemical Properties of rHSA and pHSA
Char. | pHSA | rHSA |
Amino Acids Sequence | Same | Same |
N-terminus | DAHKSEV | DAHKSEV |
C-terminus | KLVAASQAALGL | KLVAASQAALGL |
Glycosylation | No | No |
Molecular Mass(MALDI) | 66.554KD | 66.550KD |
PI | 4.8 | 4.8 |
Drug Binding | Similar | Similar |
Thermal Stability | M/P 65℃ | M/P 65℃ |
Lipid Conjugation | Identical | Identical |
Crystal Structure | Identical | Identical |
Description
The advantages of rHSA powder are as followed: First, the rHSA will not be denatured or loss its biological activity; Secondly, lyophilized products will be in the form of loose powder after drying and the color does not change. Third, rHSA powder not only facilitates the transportation but also extends the storage time of the products.The appearance of our rHSA powder is ligh beige color, which is the same as the HSA derived from plasma. The rHSA was expressed from the rice endosperm, which can fold the rHSA into the right structure and keep the stability and bioactivity of rHSA.
Advantages
Test Item | Quality Standard |
Appearance | Off-white to light beige lyophilized powder. |
PH | 6.4-7.4 |
Purity | more than 99% as determined by SDS-PAGE and HPLC analysis. |
Host cell DNA | less than 0.5ng / g protein |
Host cell protein | less than 5μg / g protein |
Sterility test | sterile |
Abnormal toxicity test | conforms to standard |
1. Wuhan Healthgen Biotechnology Corp. has been committed in research of protein purification and meanwile our technology has been patented by the US Patent and Trademark Office on May 15th 2015. "A method for isolating and purifying recombinant human serum albumin from transgenic rice grain". The patent number is US9, 023,990. The purity of our rHSA is very high. Now, our rHSA purity can be as high as 99%.
erived and refined from human plasma.
2. Healthgen Biotech recombinant human serum albumin (OsrHSA) has excellent batch consistency. Using self-pollination rice as the bioreactor to express the OsrHSA, with the world's advanced facility and top production proceeding to extract and purify the OsrHSA, Healthgen Biotech can ensure the excellent consistency of OsrHSA from different batches.
3. The rice endosperm specific expression platform is easy to be large-scale. The rice endosperm has the protein body, which can keeps proteins stability and bioactivity.
At present, the production capacity is almost 1000 kg / year.
Supplemental Description
Achievement and Honor
Healthgen Biotech obtained a number of patented technologies with independent intellectual property rights, including applied 9 national patents and 6 authorized patents, applied 7 international patents and 3 authorized patents. The international patents cover to United States, Japan, Europe and Canada. Moreover, two patents were authorized both by the Republic of South Africa and the United States. Based on rice endosperm specific expression technical platform-OryzHiExp, Healthgen Biotech, aim at the international forefront, takes the market as the orientation and enhances biotechnology innovation and engineering research, has won numerous awards.
Scientific Research Projects:
Major projects for New Drug Discovery, 3 projects of "Major projects of new varieties of genetically modified organisms” of the Ministry of Agriculture, National Ministry of Science and high Technology “863 plan”, National Ministry of Science and Technology Innovation fund, Pilot development of strategic emerging industries project
Talents Scheme:
“Thousand Talents program” of the National Central Organization Department, "Hundred Talents Program" of the Organization Department of Hubei Province, "3551 talents program” of the East Lake high-technology development zone , Top 10 "Venture Eagle" entrepreneurs.
Research Centers and Awards:
Wuhan National Biological Industry Base protein purification center, Hubei Molecular Biopharmaceutical Engineering Research Center, 2013 National Science and Technology Invention Award, 2012 Hubei Provincial Science and Technology Invention Award, 2013 China Patent Excellence Award, High-tech enterprise, Agricultural science and technology enterprise, Patent advantage enterprise.
Contact Person: Ms. Abby
Tel: +86-15071115810
Fax: 86-27-59403933-59416006