Research Recombinant Human Serum Albumin HSA Powder Industrial Biological Reagents

Research Recombinant Human Serum Albumin HSA Powder Industrial Biological Reagents

Quick detail

1. CAS No.: 70024-90-7
2. Other Names: Recombinant HSA, rHSA, OsrHSA
3. EINECS No.: 274-272-6
4. Place of Origin: Wuhan, China (Mainland)
5. Storage and Handling: Stored at temperatures 2-8℃ for 48 months
6. Purity: Greater than 99 % as determined by SDS-PAGE
7. Source: Rice Grain (Oryza Sativa)
8. Endotoxin: Less than 0.125EU/mg

Physiological and Biochemical Properties of rHSA and pHSA

Description

As the most abundant protein in human plasma, HSA is composed of 585 amino acids. It has a molecular weight of 66.5KD and an isoelectric point of 4.8. HSA is widely used in biochemical experiments, such as being used as a blocking ragent in Western Blotting. Because HSA plays a role in mailly maintaining the osmotic pressure, PH buffer and as carriers and nutritions, the rHSA can also be used as a hapten carrier, a protective reagent, and in protein complementation control in cell culture.In addition, because of the long half-life, stability and carrier funstion, rHSA is a basic reagent in the biotechnology laboratory.

Advantages 

1. Recombinant human serum albumin (rHSA) has good efficacy, such as rHSA has the same second and tertiary structure, physiological and biochemical properties with HSA from plasma. In addition, compared with HSA from plasma, rHSA has a lower immune source stimulation, and plays a better role in accelerating cell growth and metabolism, because rHSA is animal component free, which can avoid the prions or virus contaminants.

2. Healthgen Biotech recombinant human serum albumin (OsrHSA) is free of animal origin, which effectively avoid any potential risk of animal bacteria, prions, virus and contagious protein disease.

3. Wuhan Healthgen Biotechnology Corp. is a private company founded in 2006. We specialize in molecular pharmaceutical technology research and high-tech innovation-oriented product development, which is developing, manufacturing and marketing a series of recombinant proteins and growth factors by rice endosperm platform. We have 400 square meters of research center, in which 30% of the research personnels have doctoral degree and major in different directions of the research and development. Healthgen Biotech has strong capability in developing a series of biological products.

Supplemental Description 

Human serum albumin has been widely used as plasma expansion reagent. Because of its non-enzymatic activity and no immunogenicity, etc. HSA can also be used as excipient and stabilizer in a variety of pharmaceutical preparations and serum-free cell culture medium component. In addition, HSA is also used as a drug carrier due to its antioxidant properties, thereby conferring drugs better physicochemical properties. At present, most HSA products in the market are directly derived and refined from human plasma.

On the one hand, due to the potential existence of various infectious disease pathogens in the human blood, especially AIDS, hepatitis B and other viruses. Thereby, these virus from human plasma will be brought with HSA to the final products. rHSA produced by gene recombinant technology can effectlively avoid the risks of virus pollution and infection. What’s more, the supply of human blood is limited. Therefore, it’s very urgent to search blood substitutes. The establishment and development of recombinant DNA technology provide an important method for the acquisition of biological materials. In recent years, many researchers have been hotly committed to the recombinant human serum albumin research.