Higher Bioactivity Fibronectin FN For Promoting Cell Regeneration And Repairing

Higher Bioactivity Fibronectin FN Promote Cell Regeneration and Repairing

Detail

Specification

Fibronectin (FN) is a ubiquitous extracellular matrix (ECM) protein that has been implicated in many essential cell processes including wound healing and embryonic morphogenesis as well as regulation of cell behaviors such as adhesion and migration. Because of this, it is used for wound repair in medicine and as an important raw material for stem cell culture in the field of life sciences. Nowadays, FN has been an effective biological raw material for skin care due to its powerful regeneration and repair capacity. Studies have shown that FN has the effects of promoting cell metabolism, anti-oxidation, anti-aging, anti-allergic, etc. in beauty and skin care. Its main mechanism is to promote cell growth.

OsrhFN, recombinant human fibronectin which is derived from rice grain and produced by Healthgen Biotech with its core patented rice endosperm specific expression platform(Oryz^HIEXP). OsrhFN has the same functions as native FN, while it has higher bioactivity in promoting cell regeneration and repairing. The R&D of Healthgen Biotech has finished a comparative test between OsrhFN and commercial native FN with professional biological detection methods, the result shows that OsrhFN has greater efficient in promoting CHO-K1 cell adhesion and growth than commercial native FN.

Comparison of different concentrations of OsrhFn and commercial natural Fn in promoting CHO-K1 cell adhesion and growth

Supplemental Description

Healthgen Biotech, always pay great attention to the original technological innovation and intellectual property protection, has the titles of “Hubei Province Molecular Pharmaceutical Engineering Research Center” and “Protein Purification Research Center”. The rice endosperm cell high expression technology platform and other core technology have applied and gained 13 domestic and international patents; and won the “2012 Hubei Provincial Science and technology invention Award”, “2013 National Science and Technology Invention Award and China Patent Excellence Award’. The project obtained the funding from the National Ministry of science and high technology “863 plan”, Major national science and technology plan “Major projects of new varieties of genetically modified organisms” and “Major projects for new drug discovery”, the National Development and Reform Commission “Pilot development of strategic emerging industries”, National Ministry of science and technology innovation fund and state and local plans for all kinds of talented people funding.