Plant Derived Recombinant Albumin HSA 6.4-7.4 PH Lyophilized Powder

Plant Derived Recombinant Human Serum Albumin HSA 6.4-7.4 PH Lyophilized Powder

Quick detail

1. CAS No.: 70024-90-7
2. Other Names: rHSA
3. EINECS No.: 274-272-6
4. Amino Acids Sequence:the same with pHSA
5. N-terminus:DAHKSEV
6. C-terminus:KLVAASQAALGL
7. Glycosylation:No
8. PI:4.8
9. Thermal Stability:M/P 65℃
10. Lipid Conjugation:the same with pHSA
11. Crystal Structure:the same with pHSA
12. Storage and Handling: Stored at temperatures 2-8℃ for 24 months

Description

Human serum albumin is the most abundant protein in human plasma. It can transport hormones, lipds and other molecules and maintain osmotic pressure. Animal free rHSA is a recombinant human serum derived from rice grains, and doesn't contain any animal component, which is much safer than plasma derived HSA.

Advantages

1. Healthgen Biotech recombinant human serum albumin is free of animal origin, which effectively avoid any potential risk of animal bacteria, prions, virus and contagious protein disease.

2.Wuhan Healthgen Biotechnology Corp. has been committed in research of protein purification and meanwile our technology has been patented by the US Patent and Trademark Office on May 15th 2015. "A method for isolating and purifying recombinant human serum albumin from transgenic rice grain". The patent number is US9, 023,990. The purity of our rHSA is very high. Now, our rHSA purity can be as high as 99%.

3. Healthgen Biotech recombinant human serum albumin (rHSA) has excellent batch consistency. Using self-pollination rice as the bioreactor to express the rHSA, with the world's advanced facility and top production proceeding to extract and purify the rHSA, Healthgen Biotech can ensure the excellent consistency of rHSA from different batches.

4. The rice endosperm specific expression platform is easy to be large-scale. The rice endosperm has the protein body, which can keeps proteins stability and bioactivity.

At present, the production capacity is almost 1000 kg / year.

Supplemental Description

Human serum albumin has been widely used as plasma expansion reagent. Because of its non-enzymatic activity and no immunogenicity, etc. HSA can also be used as excipient and stabilizer in a variety of pharmaceutical preparations and serum-free cell culture medium component. In addition, HSA is also used as a drug carrier due to its antioxidant properties, thereby conferring drugs better physicochemical properties. At present, most HSA products in the market are directly derived and refined from human plasma.

On the one hand, due to the potential existence of various infectious disease pathogens in the human blood, especially AIDS, hepatitis B and other viruses. Thereby, these virus from human plasma will be brought with HSA to the final products. rHSA produced by gene recombinant technology can effectlively avoid the risks of virus pollution and infection. What’s more, the supply of human blood is limited. Therefore, it’s very urgent to search blood substitutes. The establishment and development of recombinant DNA technology provide an important method for the acquisition of biological materials. In recent years, many researchers have been hotly committed to the recombinant human serum albumin research.