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Formulation: | No Stabilizer Or Surface Active Agent | Endotoxin: | Less Than 0.125EU/mg |
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Production Type: | Recombinant Protein | EINECS No.: | 274-272-6 |
PH: | 6.4-7.4 | Sterility Test: | Sterile |
High Light: | PI 4.8 rHSA Cell Culture,Oryzogen rHSA Cell Culture,PI 4.8 Recombinant HSA |
PI 4.8 Human Serum Albumin HSA Cell Culture M/P 65℃ For SP2/0 Antibody Production
Quick detail
Physiological and Biochemical Properties of rHSA and pHSA
Char. | pHSA | rHSA |
Amino Acids Sequence | Same | Same |
N-terminus | DAHKSEV | DAHKSEV |
C-terminus | KLVAASQAALGL | KLVAASQAALGL |
Glycosylation | No | No |
Molecular Mass(MALDI) | 66.554KD | 66.550KD |
PI | 4.8 | 4.8 |
Drug Binding | Similar | Similar |
Thermal Stability | M/P 65℃ | M/P 65℃ |
Lipid Conjugation | Identical | Identical |
Crystal Structure | Identical | Identical |
Description
rHSA is used as a kind of necessary nutrient material in the cell culture and metabolism process. In addition, as a carrier protein, rHSA provide necessary elements for cell metabolism synthesis and transportation. In SP 2/0 cell culture, the rHSA can promote the cell growth and antibody secrection. Compared with the SP 2/0 in the FBS, the rHSA has the same result, which indicated that the rHSA has effective in the serum free medium to promote antibody secrection.
Advantages
1. Recombinant human serum albumin (OsrHSA) has good efficacy, such as OsrHSA has the same second and tertiary structure, physiological and biochemical properties with HSA from plasma. In addition, compared with HSA from plasma, OsrHSA has a lower immune source stimulation, and plays a better role in accelerating cell growth and metabolism, because OsrHSA is animal component free, which can avoid the prions or virus contaminants.
2. Healthgen Biotech recombinant human serum albumin is free of animal origin, which effectively avoid any potential risk of animal bacteria, prions, virus and contagious protein disease.
3. The rice endosperm specific expression platform is easy to be large-scale. The rice endosperm has the protein body, which can keeps proteins stability and bioactivity. At present, the production capacity is almost 1000 kg / year.
4. Healthgen Biotech quality control systerm has been certified by ISO 9001:2015 and ensure standardized process as well as qualified products.
Supplemental Description
Due to the potential existence of various infectious disease pathogens in the human blood, especially AIDS, hepatitis B and other viruses. Thereby, these virus from human plasma will be brought with HSA to the final products. rHSA produced by gene recombinant technology can effectlively avoid the risks of virus pollution and infection. What’s more, the supply of human blood is limited. Therefore, it’s very urgent to search blood substitutes. The establishment and development of recombinant DNA technology provide an important method for the acquisition of biological materials. In recent years, many researchers have been hotly committed to the recombinant human serum albumin research.
Contact Person: cjing
Tel: +8615071115810