Biopharma Recombinant Protein Service Base On Rice Cells Expression Platform

Recombinant Protein Service Base On Rice Cells expression platform​

Service Items

1. Establish process test laboratory or research services.

According to customer needs, the establishment of the simple and efficient, low cost of extraction, purification process, to provide technical solutions for the various kinds of technical problems in the production of scale.

2. To provide customers with all kinds of microbial inspection services.

Microbiological examination, microbial limit test, sterility test, total bacterial count, molds, and yeasts.

3. To provide customers with the quality of the recombinant protein.

According to the registration, the requirement is to provide the relevant physical and chemical properties, testing methods and quality standards, and other research services.

4. Ultrafiltration system: Millipore ultrafiltration system, with 10KD, 30KD, and 300KD ultrafiltration membrane package, can achieve the 0-500L scale of the material liquid concentration, dialysis, and other ultrafiltration processes.

5. Aseptic filling and lyophilization: two sets of B+ a grade a clean area freeze dry machine (0.5 cubic meters), the single batch of frozen dry capacity to reach 4-5Kg protein, can realize aseptic ingredients, filling, aseptic lyophilization, and other biological agents development process.

Service Approach

Rice endosperm cell-specific and efficient expression technology platform for protein and polypeptide expression of technical services, to achieve a stable and efficient expression of the purpose of the protein gene engineering rice lines;

at the same time, can also provide the purpose of different levels of protein and peptide purification process development and other technical services.

Services Items:

1. To provide the expression technology to express the customer’s protein.

   Target protein expression (100-1000 amino acids)

   The expression of small molecule polypeptides(less than 100 amino acids)

   The expression amount was 0.1%~0.9%for brown rice dry weight

2. Establish process test laboratory or research services.

3. To provide one-stop mode of expression from the purification process and product development services to small scale.

4. To provide the quality standard of the drug according to customer requirements.

The AKTA Protein Purification System

5 GE AKTA protein purification system, with many specifications from 0.8, 1.6, 2.6, 5 cm, column diameter and height of low pressure column chromatography, meet the demand of protein purification technology development.